deca-durabolin-9-B

durabolin 25

Drotaverine represents isoquinoline derivative which exerts a spasmolytic effect on smooth by inhibiting the enzyme phosphodiesterase IV (PDE IV). Inhibition of the enzyme phosphodiesterase IV leads to increased cAMP concentration that inactivates myosin light chain kinase (MLCK), which in turn leads to smooth muscle relaxation. Drotaverinum inhibits the enzyme phosphodiesterase  in vitro without inhibiting  isoenzymes. […]